It's crucial to understand that "biggest" is subjective and depends on factors beyond just tire size:
* Wheel offset: Different offsets will change how far the tire sticks out from the wheel well. A more negative offset pushes the tire further out, increasing the chance of rubbing.
* Tire brand and model: Even within the same size, different tires have slightly different dimensions. Some are wider or taller than others.
* Driving conditions: Off-roading or heavier loads will increase rubbing potential.
It's always recommended to check forums specific to the 2006 Tacoma, particularly those dedicated to PreRunners, for real-world experiences from owners who have tried different tire sizes. You can find many helpful discussions about tire fitment. Before committing to a purchase, you should verify that the chosen tire and wheel combination will fit your truck without modification.