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I got a 1997 Tahoe 5.7 vortec with random misfire on 6 you have went through all your basic tune procedures to replacing the injector and fuel regulator Does anybody answer?

A random misfire on cylinder #6 in a 1997 Tahoe 5.7 Vortec, even after replacing the injector and fuel regulator, points to several potential culprits. Since the basics are covered, let's delve into less common but still likely causes:

* Worn or Damaged Spark Plug and/or Wire: Even if the spark plug looks okay, it could be cracked internally or have a compromised insulator. A faulty spark plug wire can also cause intermittent misfires. Replace both the spark plug and wire for cylinder #6.

* Ignition Coil Pack: The coil pack (or individual coil if it's a DIS system) may be failing. A failing coil can cause intermittent misfires on a single cylinder. Test the coil's output using a multimeter or a dedicated ignition coil tester. A visual inspection for cracks or damage is also advisable.

* Wiring Issues: Check all the wiring leading to cylinder #6, including the connection at the coil pack, the plug wire, and the connector at the PCM (Powertrain Control Module). Look for broken insulation, corrosion, or loose connections. A simple wiggle test while the engine is running (be extremely careful!) can sometimes reveal intermittent problems.

* Valve Problem: A burnt, sticking, or damaged valve in cylinder #6 could lead to a misfire. This is less likely if it's a random misfire, but it's possible a valve is sticking intermittently. A compression test will help diagnose this. Low compression in cylinder #6 would indicate a valve issue.

* Camshaft Position Sensor (CMP) or Crankshaft Position Sensor (CKP): These sensors are crucial for ignition timing. A faulty sensor can send incorrect signals, leading to misfires. Testing these sensors requires a scan tool or multimeter.

* PCM Issues: While less likely, a problem with the PCM itself could be causing the misfire. This would be a last resort, and diagnosing PCM problems requires specialized tools and expertise.

* Vacuum Leak: A large vacuum leak could affect the air/fuel mixture, causing misfires, especially under load. Check all vacuum lines and connections for leaks.

Troubleshooting Steps:

1. Visual Inspection: Thoroughly inspect the spark plug, wire, coil pack, and all related wiring for cylinder #6.

2. Spark Test: Test for spark at the spark plug while cranking the engine. A strong, blue spark is needed.

3. Compression Test: Perform a compression test to check the cylinder's compression. Low compression suggests a mechanical issue (valves, rings, etc.).

4. Scan Tool: Use an OBD-II scan tool to check for any other diagnostic trouble codes (DTCs) besides the random misfire. A professional-level scan tool can provide more detailed data.

If you've checked all of the above and the misfire persists, it might be time to consult a qualified mechanic. They have the tools and experience to diagnose more complex issues. Remember safety first when working on your vehicle.