* Gear Ratio: Different axle ratios will significantly impact top speed.
* Tire Size: Larger tires will lower the top speed.
* Engine Condition: A well-maintained engine will likely reach a higher speed than one that's worn.
* Aerodynamics: Modifications like a roof rack or added accessories will affect aerodynamics and thus top speed.
* Weight: A heavier truck will have a lower top speed.
* Elevation and atmospheric conditions: Air density impacts engine performance.
While a stock 2003 S-10 4.3L might *theoretically* reach speeds around 100-110 mph, it's crucial to understand that this is an approximation, and achieving these speeds is dangerous and illegal. Real-world top speed will likely be lower. It's much more important to focus on safe and responsible driving practices than achieving maximum speed.