Here are some of the most likely culprits given the symptoms:
* Ignition System: This is a high probability. Misfires are often caused by problems in the ignition system. This includes:
* Spark Plugs: Worn, fouled, or damaged spark plugs are a common cause of misfires.
* Ignition Coils: A failing ignition coil (which supplies the spark to the plugs) will cause misfires in the cylinder it serves. These are especially common on the Trailblazer's 4.2L inline 6 engine.
* Ignition Wires (or Plug Wires): Cracked, frayed, or poorly connected wires can prevent a spark from reaching the plug.
* Crankshaft Position Sensor (CKP): This sensor tells the computer the engine's rotational position, crucial for proper ignition timing. A faulty CKP can lead to misfires and other issues.
* Cam Position Sensor (CMP): Similar to the CKP, a faulty CMP sensor affects timing and can cause misfires.
* Fuel System: While less likely to cause *only* misfires, problems here can exacerbate them:
* Fuel Injectors: A clogged or malfunctioning fuel injector can prevent sufficient fuel from reaching a cylinder.
* Fuel Pump: A weak fuel pump can reduce fuel pressure, leading to poor performance and misfires.
* Fuel Filter: A clogged fuel filter restricts fuel flow and can contribute to misfires.
* Mass Airflow Sensor (MAF): A faulty MAF sensor provides inaccurate readings to the computer about the air intake, leading to poor fuel mixture and misfires.
* Engine Control Module (ECM): While less common, a faulty ECM can cause a wide range of problems, including misfires. This is usually diagnosed after other components have been ruled out.
* Vacuum Leaks: A significant vacuum leak can disrupt the engine's air/fuel mixture and cause misfires. This can also affect the cruise control which relies on proper vacuum.
Why the Cruise Control Might Be Affected:
The cruise control often relies on a good vacuum signal and proper engine operation. Many of the above issues (especially vacuum leaks and some ignition problems) can interfere with this system.
What to Do:
1. Get the DTCs: This is the most important step. The codes will give you a much better idea of where to start troubleshooting.
2. Check the Obvious: Visually inspect spark plugs, wires, and ignition coils for any obvious damage.
3. Replace Spark Plugs and Wires (Often a good starting point): Even if not directly indicated by codes, these are relatively inexpensive parts and often the source of misfire problems.
4. Professional Diagnosis: If you're not comfortable working on your car yourself, take it to a qualified mechanic for diagnosis and repair.
Don't guess; the diagnostic trouble codes are your guide. Fixing the wrong part could waste time and money.