Will a 93 s10 transmission fit 01 blazer?

No, a 1993 S10 transmission will almost certainly not fit a 2001 Blazer. The transmissions, bell housings, and even the engine configurations are significantly different between those years and models. The 2001 Blazer likely has a much more modern transmission (likely a 4L60E automatic or an NV3500 manual) while the 1993 S10 used older designs. Even if you could somehow adapt the transmission, it would be a very complex and likely impractical project.