To be absolutely sure, it's best to:
* Consult your owner's manual: This is the most reliable source for the precise location.
* Use a repair manual or online diagrams: A repair manual (like a Haynes or Chilton manual) or online resources with diagrams specific to your F-150's year and engine will show you exactly where it is.
* Search online for "2000 Ford F-150 fuel filter location" with your specific engine size (e.g., 4.2L, 4.6L, 5.4L): This will yield images and descriptions from other owners who have tackled this task.
Remember to be careful when working near fuel lines, as gasoline is flammable.