* Maintenance: Regular oil changes, proper fluid levels, and timely repairs are crucial. Neglecting maintenance drastically shortens engine life.
* Driving habits: Aggressive driving, frequent short trips, and towing heavy loads put more stress on the engine.
* Operating conditions: Extreme temperatures and dusty environments can accelerate wear and tear.
* Specific engine: Different engines (e.g., 4.3L V6 vs. 2.8L V6) have different inherent strengths and weaknesses, affecting longevity.
While some S10 Blazer engines might last 200,000 miles or more with excellent care, others might need major repairs or replacement much sooner (even under 100,000 miles) due to poor maintenance or harsh use. It's not uncommon to see them reach 150,000-200,000 miles with reasonable care, but that's not a guarantee.