Do you have to take off front end of truck remove v-10 ford engine?

No, you generally don't have to remove the entire front end of a Ford truck to remove a V-10 engine. While it can make the job *easier*, it's usually possible to remove the engine with the front clip (grille, bumper, radiator, etc.) in place. Access will be tighter, and it'll be a more challenging job, but it's feasible. The exact procedure will depend on the specific year and model of the truck.