1. Heavy-duty Pickup Trucks: Full-size pickup trucks with a 400ci 6.6 liter engine typically get around 14-18 MPG in city driving and 18-22 MPG on the highway.
2. Large SUVs: Sport utility vehicles (SUVs) with a 400ci 6.6 liter engine usually achieve 12-16 MPG in city driving and 16-20 MPG on the highway.
3. Medium-duty Commercial Vehicles: Medium-duty trucks and vans with a 400ci 6.6 liter engine may get around 10-14 MPG in city driving and 14-18 MPG on the highway.
It's important to note that actual fuel efficiency can vary significantly based on factors such as traffic conditions, weather, terrain, vehicle load, and maintenance. Additionally, different vehicles equipped with the same 400ci 6.6 liter engine may have slight variations in MPG due to differences in vehicle weight, aerodynamics, and powertrain components.