* Mounting points: Ford and Oldsmobile engines have different mounting patterns. You'd need to fabricate new motor mounts.
* Transmission: The transmission bellhousing will likely be incompatible. You'll need to adapt the transmission or use a different one altogether.
* Wiring harness: The electrical systems are different. You'll need a custom wiring harness.
* Exhaust system: The exhaust system will need to be custom-made.
* Cooling system: The cooling system may require modifications.
In short, while not impossible, swapping a Ford engine into an Oldsmobile is a major undertaking requiring significant mechanical expertise, fabrication skills, and a considerable amount of time and money. It's far more complex than a simple bolt-in swap.