* Extensive Fabrication: The engine bay isn't designed for the Power Stroke. You'll need to fabricate new motor mounts, possibly modify the firewall, and create custom exhaust and intake systems. The Power Stroke is considerably larger and heavier than the V10.
* Transmission: The V10 likely uses a different transmission than the 7.3L Power Stroke. This means you'll need to source a suitable transmission (likely a 4R100 or similar) and adapt it to the Power Stroke, including the driveshaft, transfer case, and potentially the rear axle gearing. This often involves custom parts or significant modifications.
* Wiring Harness: The wiring harnesses are completely different. You'll need to either extensively modify the existing harness or source a Power Stroke harness and integrate it into the truck's system, dealing with all the related sensors, computers, and modules. This is an extremely challenging electrical task.
* Fuel System: The Power Stroke uses a completely different fuel system, including high-pressure injection. You'll need to adapt the entire fuel system, including tank, lines, filters, and injectors.
* Cooling System: The Power Stroke's cooling requirements differ significantly. You likely need a different radiator, fan, and potentially other components.
* Emissions: Meeting emission standards after the conversion will be a major hurdle, especially depending on your location's regulations.
* Cost: The cost of parts, labor, and specialized tools will be substantial.
In short: While technically possible, this conversion is a massive undertaking. It's generally considered far more practical and cost-effective to either stick with the V10 or find a 1999 F-250 that already has the 7.3L Power Stroke engine. Unless you have extensive experience with engine swaps and fabrication, it's highly recommended to leave this project to professional engine builders specializing in this type of work. Even then, it's a very challenging and time-consuming project.
