In general, the 2001 International DT466 engine is known for its durability, reliability, and fuel efficiency. However, the MPG of a vehicle with this engine can range from approximately 10 MPG to 15 MPG in city driving conditions and from 12 MPG to 18 MPG on the highway.
It's important to note that these figures are estimates and actual fuel efficiency may differ based on various circumstances and driving habits. For precise fuel efficiency information, it's best to consult the owner's manual or specific documentation for the vehicle in question.