Will a 2000 2.2L S10 supercharger fit 1995 S10?

No, a 2000 2.2L S10 supercharger will almost certainly not fit a 1995 S10. While both are 2.2L engines, there were significant changes to the engine bay and the engine itself between those model years. The supercharger is designed specifically to interface with the intake manifold, engine mounts, and other components, all of which differ between the '95 and '00 models. You'd be facing major fabrication and modification challenges, if it were even possible at all.