What *might* be relevant to your question, depending on what you're actually trying to figure out, are these things:
* Spark Plug Gap: This is the distance between the electrodes of the spark plug. This *is* a critical specification and needs to be within the manufacturer's recommended range. The correct gap for your 2005-2009 Mustang GT 4.6L V8 will depend on the *specific* spark plug you're using (e.g., Motorcraft, NGK, etc.). Consult your owner's manual or the spark plug packaging for the precise gap. This gap is usually adjusted using a spark plug gapping tool.
* Spark Plug Heat Range: This refers to how well the spark plug dissipates heat. Too cold, and fouling occurs. Too hot, and pre-ignition or detonation can happen. The correct heat range is determined by engine conditions (load, RPM, etc.), and is usually specified by the manufacturer or recommended by aftermarket part suppliers based on your car's setup (stock, modified, etc.). Again, check your owner's manual or the spark plug's specifications.
* ECU Spark Timing (Ignition Timing): This *is* calibrated, but it's not a setting *on* the spark plug itself. The Powertrain Control Module (PCM or ECU) controls the precise timing of the spark, which is crucial for engine performance and efficiency. This timing is adjusted based on numerous engine sensors and is not something you directly adjust on the spark plug. Any modification to ignition timing would be done through tuning software and an interface connected to the car's OBD-II port.
In short, if you're having issues, don't try to "calibrate" the spark plugs themselves. Focus on checking and ensuring the correct spark plug gap and heat range are used and address potential ignition timing problems through professional tuning if needed.