However, you can generally expect to see figures in the range of 12-17 MPG combined (city and highway driving). Highway driving will yield better MPG than city driving. Factors like towing a heavy load will drastically reduce fuel economy.
To get a more precise estimate, you should specify the exact year and configuration of the truck. You can then search online for fuel economy data specific to that model year. Sites like fueleconomy.gov (for US models) may provide some information.