Where is cylinder 2 on a Ford Expedition?

On a Ford Expedition, like most V8 engines, cylinder 2 is located on the passenger side (right side in the Northern Hemisphere), towards the front of the engine. It's usually the second cylinder from the front of the engine block when looking at it from the front.

However, it's impossible to be completely precise without knowing the specific year and engine configuration of the Ford Expedition. Engine layouts can vary slightly even within the same model. A diagram of your specific engine would be the most reliable source. You can usually find such diagrams in a repair manual or online using the year, make, model, and engine code.