* Engine: The 7.3L Power Stroke diesel was the most common engine in the 2000 F-250, but there might have been other options. The specific engine greatly affects fuel economy.
* Transmission: Automatic or manual transmissions will impact mileage.
* Drivetrain: 4x2 (two-wheel drive) will generally get better gas mileage than 4x4 (four-wheel drive).
* Payload and Towing: Heavier loads significantly reduce fuel economy.
* Driving style: Aggressive driving reduces fuel economy.
* Maintenance: Proper maintenance is crucial for optimal fuel efficiency.
With all these variables, it's impossible to give a single definitive answer. However, you can expect a range of 12-18 MPG for a 2000 Ford F-250 Diesel under average conditions. This is a *very* broad range. Expect lower MPG if you frequently tow heavy loads or drive in stop-and-go traffic. You'll likely see better mileage on the highway with lighter loads and smoother driving.
To get a more precise estimate, it's best to consult:
* The owner's manual: This will give the manufacturer's estimated MPG.
* Online resources: Websites like Edmunds, Kelley Blue Book, or FuelEconomy.gov might offer user-submitted fuel economy data for similar vehicles.
Keep in mind that these are just estimates, and your actual mileage may vary.
