Parking Brake Engagement: Check if the parking brake was accidentally left engaged. If so, disengage it and see if the wheel unlocks.
Brake Caliper Sticking: The brake caliper or brake pads may be stuck, preventing the wheel from rotating freely. Try to manually rotate the wheel. If it's seized or resists movement, the caliper might need servicing/repair.
Rusty Brake Components: Rust buildup on the brake components can cause them to bind and lock up. This can occur if the car is parked for extended periods without moving. Try to drive the car a short distance to see if the wheel unlocks; the movement might break away any rust.
Damaged Brake Line: A damaged or leaking brake line can cause loss of brake fluid, which can affect brake performance and potentially lead to wheel lockup. Check the brake lines for any visible signs of damage or leaks.
ABS System Issue: In some cases, problems with the vehicle's Anti-Lock Braking System (ABS) can cause wheel lockup. Check the ABS warning light on the instrument cluster. If it's illuminated, it might indicate an ABS issue.
Failed Wheel Bearing: A failed wheel bearing can cause the wheel to lock up due to excessive friction and resistance. Check for any signs of bearing damage or excessive play.
Differential Problems: Issues within the differential, where axle power is distributed to the wheels, could cause wheel lockup. Check for differential fluid leaks or any unusual noises.
Transmission Issues: In rare cases, transmission-related problems can affect wheel rotation and cause a wheel to lock up. However, this is less likely compared to the above causes.
Note: If you're unable to determine the cause and unlock the wheel yourself, it's best to consult a qualified mechanic or take the vehicle to a reputable auto repair facility for proper diagnosis and repairs.